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Discovery of a Potent and Selective NF-κB-Inducing Kinase (NIK) Inhibitor That Has Anti-inflammatory Effects in Vitro and in Vivo | Journal of Medicinal Chemistry
The Crystal Structure of the Catalytic Domain of the NF-κB Inducing Kinase Reveals a Narrow but Flexible Active Site - ScienceDirect
NIK Antibody | Cell Signaling Technology
The discovery of quinoline derivatives, as NF-κB inducing kinase (NIK) inhibitors with anti-inflammatory effects in vitro, low toxicities against T cell growth - ScienceDirect
Cells | Free Full-Text | Inhibitory-κB Kinase (IKK) α and Nuclear Factor-κB (NFκB)-Inducing Kinase (NIK) as Anti-Cancer Drug Targets
Small-molecule inhibitors of IκB kinase (IKK) and IKK-related kinases | Pharmaceutical Patent Analyst
Comprehensive profiling of the STE20 kinase family defines features essential for selective substrate targeting and signaling output | PLOS Biology
NF-κB Inducing Kinase, NIK Mediates Cigarette Smoke/TNFα-Induced Histone Acetylation and Inflammation through Differential Activation of IKKs | PLOS ONE
Nik‐related kinase is targeted for proteasomal degradation by the chaperone‐dependent ubiquitin ligase CHIP - Naito - 2020 - FEBS Letters - Wiley Online Library
Role of IκB kinase in tumorigenesis | Future Oncology
NF-κB-Inducing Kinase (NIK) Governs the Mitochondrial Respiratory Capacity, Differentiation, and Inflammatory Status of Innate Immune Cells | bioRxiv
Cells | Free Full-Text | Inhibitory-κB Kinase (IKK) α and Nuclear Factor-κB (NFκB)-Inducing Kinase (NIK) as Anti-Cancer Drug Targets
Pharmacological inhibition of NF-κB-inducing kinase (NIK) with small molecules for the treatment of human diseases - RSC Medicinal Chemistry (RSC Publishing)
NF-κB Inducing Kinase, NIK Mediates Cigarette Smoke/TNFα-Induced Histone Acetylation and Inflammation through Differential Activation of IKKs | PLOS ONE
Pharmacological inhibition of NF-κB-inducing kinase (NIK) with small molecules for the treatment of human diseases - RSC Medicinal Chemistry (RSC Publishing) DOI:10.1039/D0MD00361A
A Kinase Assay for Measuring the Activity of the NIK-IKK1 Complex Induced via the Noncanonical NF-κB Pathway | SpringerLink
MAP kinase kinase kinases and innate immunity: Trends in Immunology
A Kinase Assay for Measuring the Activity of the NIK-IKK1 Complex Induced via the Noncanonical NF-κB Pathway | SpringerLink
IJMS | Free Full-Text | Small Molecule NF-κB Pathway Inhibitors in Clinic
Frontiers | Nuclear Factor κB (NF-κB)–Mediated Inflammation in Multiple Sclerosis
Expression of noncanonical NF-kB pathway genes and NFkBeinducing kinase... | Download High-Resolution Scientific Diagram